Asthma and allergic inflammation

Cell. 2010 Mar 19;140(6):777-83. doi: 10.1016/j.cell.2010.03.004.


Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of these chronic inflammatory disorders.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Asthma / epidemiology
  • Asthma / immunology*
  • Humans
  • Immunity, Innate
  • Respiratory Hypersensitivity / epidemiology
  • Respiratory Hypersensitivity / immunology*
  • Respiratory Mucosa / immunology*