Brainstem dysgenesis in an infant prenatally exposed to cocaine

Pediatr Neurol. 2010 Apr;42(4):295-7. doi: 10.1016/j.pediatrneurol.2009.11.009.


Many authors described the effects on the fetus of maternal cocaine abuse during pregnancy. Vasoconstriction appears to be the common mechanism of action leading to a wide range of fetal anomalies. We report on an infant with multiple cranial-nerve involvement attributable to brainstem dysgenesis, born to a cocaine-addicted mother.

Publication types

  • Case Reports

MeSH terms

  • Brain Stem / abnormalities*
  • Brain Stem / drug effects*
  • Brain Stem / pathology
  • Cocaine / toxicity*
  • Cranial Nerve Diseases / chemically induced*
  • Cranial Nerve Diseases / pathology
  • Dopamine Uptake Inhibitors / toxicity*
  • Fatal Outcome
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Male


  • Dopamine Uptake Inhibitors
  • Cocaine