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. 2010 Apr;46(3-4):173-7.
doi: 10.1007/s11626-010-9283-5. Epub 2010 Mar 24.

Derivation and Characterisation of the Human Embryonic Stem Cell Line, OxF1

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Derivation and Characterisation of the Human Embryonic Stem Cell Line, OxF1

Frances Anne Brook et al. In Vitro Cell Dev Biol Anim. .

Abstract

OxF1 is a human embryonic stem cell line derived from a surplus embryo donated through the Oxford IVF clinic. The cells have a stable 46 XX karyotype and show expression of Oct 4, Nanog and TRA-1-60. Embryoid bodies differentiate into cells that represent all three germ layers as demonstrated by immunohistochemical localisation of beta III tubulin, nestin, desmin, smooth muscle actin, Gata 6 and cytokeratin 18. Directed differentiation through haematopoiesis has been demonstrated.

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References

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