Vaccination strategies against myxomavirus infections: are we really doing the best?

Tijdschr Diergeneeskd. 2010 Mar 1;135(5):194-8.

Abstract

Vaccination is the best way to control myxomatosis in both pet and production rabbits. Two types of myxomatosis vaccines are commercially available, namely, a vaccine prepared from the Shope fibroma virus (SFV) and one prepared from an attenuated myxoma virus (MV) strain, e.g., SG33. The first one is weakly immunogenic and provides only short-term protection whereas atypical reactions have been described with the second one. This short review describes the vaccine strains and provides some data on the host-virus relationship, resistance, and immunity in myxomatosis. In the last section, recommended myxomatosis vaccination schemes for production and pet animals are presented.

Publication types

  • Review

MeSH terms

  • Animals
  • Antibodies, Viral / blood
  • Antiviral Agents / therapeutic use*
  • Drug Resistance, Viral
  • Host-Pathogen Interactions
  • Immunization Schedule
  • Myxoma virus / immunology*
  • Myxoma virus / pathogenicity
  • Myxomatosis, Infectious / drug therapy
  • Myxomatosis, Infectious / prevention & control*
  • Myxomatosis, Infectious / virology*
  • Rabbits / virology*
  • Vaccination / veterinary*
  • Viral Vaccines / administration & dosage*

Substances

  • Antibodies, Viral
  • Antiviral Agents
  • Viral Vaccines