[Effect of ozone water on the inflammation and repair in infected wounds]

Nan Fang Yi Ke Da Xue Xue Bao. 2010 Mar;30(3):515-8.
[Article in Chinese]

Abstract

Objective: To study the effect of ozone water in promoting the healing of infected wounds.

Methods: Fifty Wistar rats were randomly divided into 5 groups, namely chlorhexidine treatment group, 5, 10, and 20 mg/L ozone water treatment groups, and the control group without any treatment. Infected wounds were induced on the back of the rats, and at 48 h of infection, chlorhexidine or ozone water was applied once daily for 9 days. Before and at days 3, 6, and 9 of the treatment, the wound changes were observed. The WBC in the tail venous blood was detected and the incised skin and muscular tissues were pathologically examined. RESULTS AMD CONCLUSION: Ozone water showed better effects in promoting the healing of the infected wound, especially at higher doses of 10 and 20 mg/L.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Female
  • Inflammation / drug therapy
  • Male
  • Ozone / therapeutic use*
  • Random Allocation
  • Rats
  • Rats, Wistar
  • Wound Healing / drug effects*
  • Wound Infection / drug therapy*

Substances

  • Ozone