[Perioperative acquired long QT syndrome: a case report]

Rev Esp Anestesiol Reanim. 2010 Feb;57(2):109-14. doi: 10.1016/s0034-9356(10)70173-0.
[Article in Spanish]

Abstract

Acquired long QT syndrome is a rare condition whose diagnosis is of vital importance given the risk of torsade de pointes and sudden death. This syndrome may be triggered by various events in patients with a genetic predisposition. Patients usually have a normal baseline QT interval. Some of the factors that may prolong the interval are exposure to common drugs such as antibiotics or agents used for general anesthesia. Diagnosis of the condition is essential, as is knowledge of how to manage anesthesia and prevent ventricular fibrillation, which is the most feared complication. We report the case of a man with no relevant medical history who underwent emergency surgery for a peritonsillar abscess. The patient developed long QT syndrome, with several episodes of torsade de pointes and cardiorespiratory arrest.

Publication types

  • Case Reports

MeSH terms

  • Adjuvants, Anesthesia / adverse effects
  • Adrenergic beta-Antagonists / therapeutic use
  • Amoxicillin-Potassium Clavulanate Combination / therapeutic use
  • Anesthetics, Inhalation / adverse effects
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / adverse effects
  • Anti-Infective Agents / pharmacology
  • Anti-Infective Agents / therapeutic use
  • Combined Modality Therapy
  • Drainage
  • Electric Countershock
  • Heart Arrest / etiology*
  • Heart Arrest / therapy
  • Humans
  • Long QT Syndrome / drug therapy
  • Long QT Syndrome / etiology*
  • Male
  • Methyl Ethers / adverse effects
  • Metronidazole / adverse effects
  • Metronidazole / pharmacology
  • Metronidazole / therapeutic use
  • Middle Aged
  • Peritonsillar Abscess / complications
  • Peritonsillar Abscess / drug therapy
  • Peritonsillar Abscess / surgery*
  • Postoperative Complications / drug therapy
  • Postoperative Complications / etiology*
  • Quaternary Ammonium Compounds / adverse effects
  • Sevoflurane
  • Torsades de Pointes / drug therapy
  • Torsades de Pointes / etiology*
  • Ventricular Fibrillation / etiology*
  • Ventricular Fibrillation / therapy

Substances

  • Adjuvants, Anesthesia
  • Adrenergic beta-Antagonists
  • Anesthetics, Inhalation
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Methyl Ethers
  • Quaternary Ammonium Compounds
  • Metronidazole
  • Sevoflurane
  • Amoxicillin-Potassium Clavulanate Combination