A comparison of the acceptance of immunochemical faecal occult blood test and colonoscopy in colorectal cancer screening: a prospective study among Chinese

Aliment Pharmacol Ther. 2010 Jul;32(1):74-82. doi: 10.1111/j.1365-2036.2010.04312.x. Epub 2010 Mar 25.

Abstract

Background: Preferences to choose immunochemical faecal occult blood test (FIT) and colonoscopy as colorectal cancer (CRC) screening modalities among asymptomatic Chinese subjects remain unknown.

Aim: To evaluate the preference of choosing colonoscopy vs. FIT among CRC screening participants.

Methods: From a community-based CRC screening programme for asymptomatic Hong Kong Chinese aged 50-70 years, participants attended standardized educational sessions and chose the options of annual FIT for 5 years or direct colonoscopy once. Factors associated with choosing colonoscopy were evaluated by multivariate regression analysis.

Results: Among 3430 participants [mean age 56.8 years (s.d. 5.0); female 55.1%, male 44.9%], 51.3% chose colonoscopy and 48.7% chose FIT. Older participants (65-70 years) were less likely to choose colonoscopy [adjusted odds ratio (aOR) 0.731, P = 0.041]. Subjects who chose colonoscopy were those disagreed screening would lead to discomfort (aOR 1.356, P < 0.001), had relatives or friends who had CRC (first degree relatives aOR 1.679, P < 0.001; second degree relatives aOR 1.304, P = 0.019; friends or others aOR 1.252, P = 0.026) and those who self-perceived their health as poor (aOR 1.529, P = 0.025).

Conclusions: Faecal occult blood test and direct colonoscopy were equally preferable to Chinese. Colonoscopy was preferred among the younger subjects, those with positive family history of CRC and self-perceived poor health status.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Asian Continental Ancestry Group
  • Colonoscopy / methods*
  • Colonoscopy / psychology
  • Colorectal Neoplasms / diagnosis*
  • Early Detection of Cancer / methods*
  • Early Detection of Cancer / psychology
  • Female
  • Hong Kong
  • Humans
  • Male
  • Middle Aged
  • Occult Blood*
  • Patient Acceptance of Health Care / psychology
  • Prospective Studies
  • Regression Analysis