Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 14 (3), 298-313

Induction Therapy: Why, When, and Which Agent?

Affiliations
Review

Induction Therapy: Why, When, and Which Agent?

Leah Krischock et al. Pediatr Transplant.

Abstract

The long-term outcome of paediatric transplantation has improved over the last decade with an increase in the armamentarium of immunosuppressive agents. However, the battle against the hostile immune response at the time of and after transplantation continues. Induction therapy can reduce early injury, to optimize the long-term allograft survival. The goal of induction immunosuppression in paediatric transplantation is to permit the use of lower doses of maintenance immunosuppressive agents without increased rates of acute allograft rejection and chronic allograft damage. The aim of this review is to summarize the current literature relating to the use of antibody agents for induction in paediatric solid organ transplantation.

Similar articles

See all similar articles

MeSH terms

LinkOut - more resources

Feedback