Abstract
A review of the design and synthesis of structural analogs of the vitamin D hormone recently investigated in our laboratories, and the first report on a new class of vitamin D analogs characterized by an aromatic D-ring, is described.
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Apoptosis
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Benzene / chemistry
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Carbon / chemistry
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Catalysis
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Cattle
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Chemistry, Pharmaceutical / methods
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Dimerization
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Drug Design
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Humans
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Models, Chemical
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Neovascularization, Pathologic
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Receptors, Calcitriol / chemistry
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Structure-Activity Relationship
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Vitamin D / analogs & derivatives*
Substances
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Receptors, Calcitriol
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Vitamin D
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Carbon
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Benzene