ALPS-ten lessons from an international workshop on a genetic disease of apoptosis

Michael J Lenardo; João B Oliveira; Lixin Zheng; V Koneti Rao

doi:10.1016/j.immuni.2010.03.013

ALPS-ten lessons from an international workshop on a genetic disease of apoptosis

Immunity. 2010 Mar 26;32(3):291-5. doi: 10.1016/j.immuni.2010.03.013.

Authors

Michael J Lenardo¹, João B Oliveira, Lixin Zheng, V Koneti Rao

Affiliation

¹ Molecular Development Section, Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892, USA. mlenardo@niaid.nih.gov

Abstract

An international group of researchers investigating the molecular, cellular, immunological, and clinical aspects of the autoimmune lymphoproliferative syndrome (ALPS) met in Bethesda, Maryland on September 21-22, 2009 to discuss advances made over the past 15 years. Their discussions yielded ten broad messages applicable to genetic and immunological investigations of human disease.

Publication types

Congress
Research Support, N.I.H., Intramural

MeSH terms

Animals
Apoptosis*
Autoimmune Lymphoproliferative Syndrome / genetics*
Autoimmune Lymphoproliferative Syndrome / immunology
Genetic Predisposition to Disease
Humans
Mutation

Grant support

Z01 AI000769-12/ImNIH/Intramural NIH HHS/United States