ALPS-ten lessons from an international workshop on a genetic disease of apoptosis

Immunity. 2010 Mar 26;32(3):291-5. doi: 10.1016/j.immuni.2010.03.013.


An international group of researchers investigating the molecular, cellular, immunological, and clinical aspects of the autoimmune lymphoproliferative syndrome (ALPS) met in Bethesda, Maryland on September 21-22, 2009 to discuss advances made over the past 15 years. Their discussions yielded ten broad messages applicable to genetic and immunological investigations of human disease.

Publication types

  • Congress
  • Research Support, N.I.H., Intramural

MeSH terms

  • Animals
  • Apoptosis*
  • Autoimmune Lymphoproliferative Syndrome / genetics*
  • Autoimmune Lymphoproliferative Syndrome / immunology
  • Genetic Predisposition to Disease
  • Humans
  • Mutation