Bilateral juvenile choroidal neovascularization associated with Best's vitelliform dystrophy: observation versus photodynamic therapy

J Pediatr Ophthalmol Strabismus. 2010 Mar-Apr;47(2):121-2. doi: 10.3928/01913913-20100308-14. Epub 2010 Mar 22.


The authors recently observed a boy with bilateral choroidal neovascularization associated with Best's disease and compared the outcome of photodynamic therapy in one eye with the natural history of the untreated fellow eye. The final outcome of photodynamic therapy was inactive choroidal neovascularization, which seemed to be enveloped by the retinal pigment epithelium. The final appearance of the treated lesion was similar to the natural evolution of choroidal neovascularization in the untreated fellow eye.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Choroidal Neovascularization / diagnosis
  • Choroidal Neovascularization / etiology*
  • Choroidal Neovascularization / therapy
  • Corneal Dystrophies, Hereditary / complications*
  • Corneal Dystrophies, Hereditary / diagnosis
  • Diagnosis, Differential
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Macula Lutea / pathology*
  • Male
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use*
  • Porphyrins / therapeutic use*
  • Verteporfin
  • Visual Acuity


  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin