Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents

J Med Chem. 2010 Jul 22;53(14):5085-107. doi: 10.1021/jm100062h.

Publication types

  • Review

MeSH terms

  • Analgesics / chemistry
  • Analgesics / pharmacology*
  • Analgesics / therapeutic use
  • Animals
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology*
  • Anti-Inflammatory Agents / therapeutic use
  • Asthma / drug therapy
  • Asthma / metabolism
  • Humans
  • Ion Channel Gating
  • Neurons / metabolism
  • Pain / drug therapy
  • Pain / metabolism
  • Peripheral Nervous System Diseases / drug therapy
  • Peripheral Nervous System Diseases / metabolism
  • Pulmonary Disease, Chronic Obstructive / drug therapy
  • Pulmonary Disease, Chronic Obstructive / metabolism
  • Transient Receptor Potential Channels / agonists*
  • Transient Receptor Potential Channels / antagonists & inhibitors*
  • Transient Receptor Potential Channels / physiology

Substances

  • Analgesics
  • Anti-Inflammatory Agents
  • Transient Receptor Potential Channels