[The effect of NaCl solution with different concentration on the resuscitation of hemorrhagic shock]

Zhonghua Yi Xue Za Zhi. 2010 Jan 19;90(3):201-4.
[Article in Chinese]

Abstract

Objective: To observe the clinical results of different concentration NaCl solution in hemorrhagic shock resuscitation.

Methods: The 75 cases with hemorrhagic shock were divided into five groups by means of random number table. Treat the cases with 0.9% (control group), 3%, 4.5%, 6% and 7.5% NaCl solution, respectively. Observe the changes of BP, HR, blood gas, renal function, electrolyte concentration of plasma, before and after treatment.

Results: After transfusion, compared with groups of 0.9% NS, the mean BP of patients in other four groups rise more quickly but only the group of 4.5% can last 30 minutes (P < 0.05), and K(+) of plasma in groups of 6%, 7.5% NS decline more obviously (P < 0.05), the group of 4.5% maintain the best lever.

Conclusion: The mean BP of patients rise quickly and continue for a long time, in the group of 4.5%. Meanwhile the internal environment of the body maintain relatively stable in the group of 4.5%.

Publication types

  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Saline Solution, Hypertonic / administration & dosage
  • Shock, Hemorrhagic / therapy*
  • Sodium Chloride / administration & dosage*
  • Treatment Outcome
  • Young Adult

Substances

  • Saline Solution, Hypertonic
  • Sodium Chloride