An adult onset Still's disease mimicking pneumonia

Rheumatol Int. 2012 Aug;32(8):2539-41. doi: 10.1007/s00296-010-1445-y. Epub 2010 Apr 2.


Adult onset Still's disease is a rare systemic inflammatory disease of unknown origin. It is common to involve liver and spleen, and less often lungs. A 24-year-old man presenting with spiking fever, pulmonary infiltrations, and pleural effusion on the right side mimicking pneumonia. All serologic tests of infectious causes, antinuclear antibody, and rheumatoid factor were negative. He was diagnosed as Adult onset Still's disease according to the criteria of Yamaguchi. Adult onset Still's disease is considering in the differential diagnosis pneumonia that is unresponsive to antimicrobial treatment, negative cultures and serologically diagnostic laboratory tests, and high-level serum ferritin.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Infective Agents / therapeutic use
  • Biomarkers / blood
  • Cough / etiology
  • Diagnosis, Differential
  • Fever / etiology
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Leukocytosis / etiology
  • Male
  • Pleural Effusion / etiology
  • Pneumonia / complications
  • Pneumonia / diagnosis*
  • Pneumonia / drug therapy
  • Predictive Value of Tests
  • Still's Disease, Adult-Onset / blood
  • Still's Disease, Adult-Onset / complications
  • Still's Disease, Adult-Onset / diagnosis*
  • Still's Disease, Adult-Onset / drug therapy
  • Treatment Outcome


  • Anti-Infective Agents
  • Biomarkers
  • Glucocorticoids
  • Immunosuppressive Agents