Pediatric kidney transplantation

Pediatr Clin North Am. 2010 Apr;57(2):393-400, table of contents. doi: 10.1016/j.pcl.2010.01.016.


Kidney transplantation in pediatric patients has become a routinely successful procedure, with 1- and 5-year patient survival rates of 98% and 94%, and 1- and 5-year graft survival rates of 93% to 95% and 77% to 85% (the range takes into account differences between living and deceased donors). These good outcomes represent the cumulative effect of improvements in pre- and posttransplant patient care, operative techniques, immunosuppression, and infection prophylaxis, diagnosis, and treatment. This article provides a brief historical overview, discusses the indications for transplantation, describes the evaluation process for the recipient and the potential donor, outlines the operative details, reviews the various causes of and risk factors for graft dysfunction, and analyzes outcomes.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Child
  • History, 20th Century
  • Humans
  • Kidney Transplantation* / adverse effects
  • Kidney Transplantation* / history
  • Kidney Transplantation* / methods
  • Kidney Transplantation* / trends
  • Patient Selection
  • Research
  • Risk Factors
  • Transplantation Immunology
  • Treatment Outcome