The X chromosome of marsupials shares a highly conserved region with eutherians

Genomics. 1991 Apr;9(4):598-604. doi: 10.1016/0888-7543(91)90352-f.


Ten genes, located on the long arm of the human X chromosome, were mapped in several marsupial species by somatic cell analysis and in situ hybridization. All were located on the X chromosome in each species. We conclude that the long arm of the human X chromosome represents a highly conserved region that formed part of the X chromosome in a therian ancestor 120-150 million years ago, before the mammalian infraclasses diverged.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biological Evolution*
  • Blotting, Southern
  • Cell Line
  • Chromosome Mapping
  • Humans
  • Hybrid Cells
  • Marsupialia / genetics*
  • Nucleic Acid Hybridization
  • Rodentia
  • X Chromosome*