The long-term effects of mindfulness-based cognitive therapy as a relapse prevention treatment for major depressive disorder

Behav Cogn Psychother. 2010 Oct;38(5):561-76. doi: 10.1017/S135246581000010X. Epub 2010 Apr 7.

Abstract

Background: Mindfulness-based Cognitive Therapy (MBCT) is a relapse prevention treatment for major depressive disorder.

Method: An observational clinical audit of 39 participants explored the long-term effects of MBCT using standardized measures of depression (BDI-II), rumination (RSS), and mindfulness (MAAS).

Results: MBCT was associated with statistically significant reductions in depression from pre to post treatment. Gains were maintained over time (Group 1, 1-12 months, p = .002; Group 2, 13-24 months, p = .001; Group 3, 25-34 months, p = .04). Depression scores in Group 3 did begin to worsen, yet were still within the mild range of the BDI-II. Treatment variables such as attendance at "booster" sessions and ongoing mindfulness practice correlated with better depression outcomes (p = .003 and p = .03 respectively). There was a strong negative correlation between rumination and mindful attention (p < .001), consistent with a proposed mechanism of metacognition in the efficacy of MBCT.

Conclusion: It is suggested that ongoing MBCT skills and practice may be important for relapse prevention over the longer term. Larger randomized studies of the mechanisms of MBCT with longer follow-up periods are recommended.

MeSH terms

  • Adult
  • Aged
  • Chronic Disease
  • Cognitive Behavioral Therapy / methods*
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / prevention & control
  • Depressive Disorder, Major / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Long-Term Care
  • Male
  • Meditation / psychology*
  • Middle Aged
  • Personality Inventory / statistics & numerical data
  • Psychometrics
  • Psychotherapy, Group / methods*
  • Retreatment
  • Secondary Prevention