Abstract
That adult humans possess active brown adipose tissue potentially leads to a paradigm shift in the understanding of human metabolism and of obesity. Adaptive adrenergic thermogenesis in humans represents brown adipose tissue activity, the absence of which may contribute to middle-age obesity.
2010 Elsevier Inc. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adipose Tissue, Brown / physiology*
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Aging / physiology*
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Energy Metabolism / physiology*
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Humans
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Ion Channels / metabolism*
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Leptin / metabolism
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Mitochondrial Proteins / metabolism*
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Models, Biological
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Obesity / etiology*
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Obesity / physiopathology
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Thermogenesis / physiology*
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Uncoupling Protein 1
Substances
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Ion Channels
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Leptin
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Mitochondrial Proteins
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Uncoupling Protein 1