Immunosuppressive drugs in immune and inflammatory ocular disease

Surv Ophthalmol. Mar-Apr 1991;35(5):369-85. doi: 10.1016/0039-6257(91)90186-j.


Advances in immunology, particularly ocular immunology, have been accompanied by the emergence of safer, more specific immunosuppressive drugs, notably, cyclophosphamide, chlorambucil, methotrexate, azathioprine, cyclosporine A, bromocriptine, dapsone, and colchicine. These drugs have become an important, and often essential, part of the ophthalmologist's armamentarium against inflammatory and immune-mediated ocular diseases. In order to better acquaint the ophthalmologist with the properties of the most commonly used immunosuppressive drugs, we review the literature and relate our own experience with these agents.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Autoimmune Diseases / drug therapy*
  • Endophthalmitis / drug therapy*
  • Eye Diseases / drug therapy*
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*


  • Immunosuppressive Agents