Repaglinide induced acute hepototoxicity

JNMA J Nepal Med Assoc. 2009 Apr-Jun;48(174):162-4.

Abstract

Repaglinide is considered a safe drug; adverse events are mild to moderate which includes hypoglycemia, headache, nausea, vomiting, diarrhea and dyspepsia as similar to sulphonylureas. This case report describes a rare side effect of repaglinide. In rare cases, elevated liver enzymes have been noted. We report a case of acute hepatotoxicity in a 78-year-old woman who developed acute hepatotoxicity while taking repaglinide.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Aged
  • Carbamates / administration & dosage
  • Carbamates / adverse effects*
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / etiology*
  • Cholangiopancreatography, Magnetic Resonance
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diagnosis, Differential
  • Female
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / adverse effects*
  • Piperidines / administration & dosage
  • Piperidines / adverse effects*

Substances

  • Carbamates
  • Hypoglycemic Agents
  • Piperidines
  • repaglinide