Saccharide effects on cognition and well-being in middle-aged adults: a randomized controlled trial

Dev Neuropsychol. 2010;35(1):66-80. doi: 10.1080/87565640903325709.


The current study used a randomized, double-blind, placebo-controlled design to investigate the effects of saccharide supplementation on cognition and well-being in middle-aged adults. Participants (N = 109; 45-60 years) took a teaspoon of a combination of saccharides or a placebo twice daily for 12 weeks (3.6 g per day). Before and after this supplementation period, participants completed alternate forms of standardized tests of cognition and self-report measures of well-being. Significant beneficial effects of saccharide supplementation were found for memory performance and indicators of well-being. The potential for these nutrients to optimize cognitive function and well-being in older adults warrants ongoing investigation.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Activities of Daily Living
  • Analysis of Variance
  • Attention / drug effects
  • Carbohydrates / administration & dosage*
  • Cognition / drug effects*
  • Dietary Supplements*
  • Double-Blind Method
  • Female
  • Health Status*
  • Humans
  • Male
  • Memory / drug effects
  • Middle Aged
  • Neuropsychological Tests
  • Self Concept
  • Surveys and Questionnaires
  • Time Factors


  • Carbohydrates