Recording isoniazid preventive therapy delivery to children: operational challenges

Int J Tuberc Lung Dis. 2010 May;14(5):650-3.


Despite recommendations to provide isoniazid preventive therapy (IPT) to eligible children aged <5 years who are in close contact with an infectious tuberculosis (TB) case, IPT delivery in high-burden settings remains poor. To evaluate the current system supporting IPT delivery to children in an urban community, South Africa, we reviewed the recording practices of a local clinic regarding management of children exposed to a current adult TB case. No standardised IPT management tools existed. Only 21% of children eligible for IPT had documentation of IPT delivery. There is a need to implement systems that support IPT recommendations in high-burden settings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use*
  • Child, Preschool
  • Documentation
  • Family Characteristics
  • Female
  • Humans
  • Isoniazid / therapeutic use*
  • Male
  • Middle Aged
  • Practice Guidelines as Topic*
  • Registries
  • South Africa / epidemiology
  • Tuberculosis / epidemiology
  • Tuberculosis / prevention & control*
  • Urban Health Services / organization & administration
  • Young Adult


  • Antitubercular Agents
  • Isoniazid