Modified Kenneth Jones criteria for diagnosing tuberculous meningitis in children

J Coll Physicians Surg Pak. 2010 Apr;20(4):258-61.


Objective: To evaluate accuracy of modified Kenneth Jones scoring criteria (MKJSC) as a screening tool to diagnose tuberculous meningitis in children.

Study design: Cross-sectional study.

Place and duration of study: Paediatric Medicine, Unit-I, Bahawal Victoria Hospital, Bahawalpur, from May 2006 to March 2007.

Methodology: A total of 100 children admitted through emergency in Paediatric Medicine, Unit-I, were included who were having fever and features suggestive of central nervous system (CNS) infection. Lumbar puncture was done in all patients after written consent. Findings of lumbar puncture were taken as gold standard for the diagnosis of TBM. MKJSC was applied on each patient and accuracy determined against the gold standard.

Results: Out of 100 children, 47 were diagnosed as TBM on the basis of CSF results. All children had scored 0-7 or above according to MKJSC. A score 1-2, 3-4, 5-6 and 7 or more was obtained in 23, 25, 30 and 22 children respectively. Children who had scored 5 or more received ATT. Accuracy of MKJSC was calculated to be 91%.

Conclusion: MKJSC is a simple and accurate tool to improve tuberculous meningitis case detection rate in children.

Publication types

  • Evaluation Study

MeSH terms

  • Age Factors
  • Antitubercular Agents / therapeutic use
  • Child, Preschool
  • Cross-Sectional Studies
  • Decision Support Techniques
  • Diagnosis, Differential
  • Female
  • Health Status Indicators
  • Humans
  • Male
  • Mycobacterium tuberculosis
  • Prognosis
  • Sensitivity and Specificity
  • Spinal Puncture
  • Tuberculosis, Meningeal / diagnosis*
  • Tuberculosis, Meningeal / drug therapy
  • Tuberculosis, Meningeal / microbiology


  • Antitubercular Agents