Factor analysis of behavioural symptoms in Huntington's disease

J Neurol Neurosurg Psychiatry. 2011 Apr;82(4):411-2. doi: 10.1136/jnnp.2009.181149. Epub 2010 Apr 14.


A principal-components factor analysis was performed on behavioural data obtained from the European Huntington's Disease Network REGISTRY study. 1690 valid assessments using the United Huntington's Disease Rating Scale Behavioural Rating Scale were included in the analysis. This large data set confirmed previous reports of distinct behavioural patterns within Huntington's disease comprising a depressive factor, a dysexecutive factor, an irritability factor and a psychosis factor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Behavioral Symptoms / complications
  • Behavioral Symptoms / psychology*
  • Depression / complications
  • Executive Function
  • Factor Analysis, Statistical
  • Humans
  • Huntington Disease / complications
  • Huntington Disease / diagnosis
  • Huntington Disease / psychology*
  • Irritable Mood
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / complications