Biliary patency imaging after endoscopic retrograde sphincterotomy with gallbladder in situ. Clinical impact of nonvisualization

Arch Surg. 1991 Jun;126(6):738-41; discussion 741-2. doi: 10.1001/archsurg.1991.01410300084012.


We prospectively performed nuclear biliary patency imaging (HIDA scanning) in 62 patients who had undergone endoscopic retrograde sphincterotomy for management of pancreaticobiliary disease with their gallbladders in situ. Elective cholecystectomy was not recommended because of advanced age, comorbidity, or absence of gallstones. All patients had patent cystic ducts at endoscopic retrograde cholangiopancreatography balloon cholangiography. Eighteen (29.1%) of 62 patients had nonvisualizing HIDA scans, and in 44 (70.9%) of 62 visualization was normal or delayed. Six cholecystectomies were required for colic (n = 1), acute cholecystitis (n = 4), and acute cholecystocholedochal fistula with cholangitis (n = 1). Among the patients with cholelithiasis and nonvisualization (n = 13), five (38.5%) required surgery, whereas only one (4.8%) of 21 patients with cholelithiasis and visualization required surgery. Nonvisualizing HIDA scans are frequent (30%) after endoscopic retrograde sphincterotomy and have no clinical relevance in patients without cholelithiasis but predict the need for cholecystectomy within 16 months in 38.5% of patients with cholelithiasis.

MeSH terms

  • Aged
  • Cholangiopancreatography, Endoscopic Retrograde
  • Cholecystectomy
  • Cholelithiasis / diagnostic imaging
  • Cholestasis, Extrahepatic / diagnostic imaging
  • Cystic Duct / diagnostic imaging*
  • Cystic Duct / physiology
  • Female
  • Follow-Up Studies
  • Gallbladder / diagnostic imaging*
  • Gallstones / surgery
  • Humans
  • Imino Acids
  • Male
  • Organotechnetium Compounds
  • Radionuclide Imaging
  • Sphincterotomy, Transduodenal*
  • Technetium Tc 99m Lidofenin


  • Imino Acids
  • Organotechnetium Compounds
  • Technetium Tc 99m Lidofenin