Long-term potency after early use of a vacuum erection device following radical prostatectomy

BJU Int. 2010 Dec;106(11):1719-22. doi: 10.1111/j.1464-410X.2010.09360.x.


Objective: To evaluate the long-term potency after radical prostatectomy (RP) with the early use of a vacuum erection device (VED), and reasons for sexual inactivity and long-term attrition and maintenance of sexual activity, as RP is one of the most common treatments for prostate cancer but erectile dysfunction (ED) is a common side-effect.

Patients and methods: We identified 141 sexually active patients who underwent RP at Cleveland Clinic Foundation. Patients were offered various non-oral treatment options to prevent ED and were also motivated for early penile rehabilitation. At 5 years 62% remained sexually active, of whom 71% had natural erections sufficient for intercourse without assistance, 8.5% were still using sildenafil, 10% were using combined therapy (sildenafil plus VED). At 5 years 38% (43/113) men were sexually inactive. The reasons included loss of interest in 17 (40%), cardiovascular/neurological diseases in 18 (42%), hormonal therapy in three (7%), loss of partner in three (7%) and two had other surgery. The natural rate of erections for sufficient vaginal penetration without an erection aid were preserved and maintained in the early-prophylaxis group, and almost 60% of them had used a VED as early prophylaxis.

Conclusion: Despite current phosphodiesterase-5 inhibitor treatments for ED, VED is becoming recognized again as having a primary role in early penile rehabilitation in many patients, specifically those treated for prostate cancer.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Humans
  • Impotence, Vasculogenic / prevention & control*
  • Male
  • Middle Aged
  • Penile Erection / physiology*
  • Penile Prosthesis*
  • Prostatectomy / adverse effects
  • Prostatectomy / rehabilitation*
  • Prostatic Neoplasms / rehabilitation*
  • Prostatic Neoplasms / surgery
  • Time Factors
  • Treatment Outcome
  • Vacuum