Surveillance of invasive pneumococcal disease in 30 EU countries: Towards a European system?

Vaccine. 2010 May 21;28(23):3920-8. doi: 10.1016/j.vaccine.2010.03.069. Epub 2010 Apr 13.


In this era of new pneumococcal conjugate vaccines (PCV), we described and compared surveillance of invasive pneumococcal disease (IPD) and PCV policies in 30 European countries to provide guidance for Europe-wide surveillance. We confirmed the heterogeneity of surveillance systems and case definitions across countries but identified elements common to all countries, such as the availability of serotyping and the surveillance of pneumococcal meningitis. PCV impact was monitored in 11/15 countries using it. We propose steps for the monitoring of incidence rates and serotype distribution at EU level, to assess the need to introduce PCV and monitor its impact once introduced.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Notification
  • Europe / epidemiology
  • Humans
  • Immunization Programs
  • Incidence
  • Meningitis, Pneumococcal / epidemiology
  • Pneumococcal Infections / epidemiology*
  • Pneumococcal Vaccines / administration & dosage
  • Population Surveillance / methods*
  • Serotyping
  • Vaccines, Conjugate / administration & dosage


  • Pneumococcal Vaccines
  • Vaccines, Conjugate