Limited diagnostic value of unilateral sacroiliitis in scintigraphy in assessing axial spondyloarthritis

J Rheumatol. 2010 Jun;37(6):1200-2. doi: 10.3899/jrheum.091216. Epub 2010 Apr 15.

Abstract

Objective: To assess the diagnostic value for axial spondyloarthritis (SpA) of unilateral sacroiliitis in scintigraphy in daily clinical practice.

Methods: In 207 patients with chronic back pain, the diagnostic value of scintigraphy was assessed retrospectively. The diagnosis made by the rheumatologist (axial SpA vs no axial SpA) was the standard.

Results: Sensitivities of scintigraphy for any (unilateral or bilateral), bilateral, and isolated unilateral sacroiliitis were 64.9%, 40.2%, and 24.7%, respectively. Respective specificities were 50.5%, 57.7%, and 92.8%, resulting in likelihood ratios of 1.3, 1.0, and 3.4.

Conclusion: Scintigraphy of the sacroiliac joints is of limited value for the diagnosis of axial SpA. Unilateral compared to bilateral sacroiliitis is slightly superior, but is associated with a low sensitivity.

MeSH terms

  • Adult
  • Female
  • Humans
  • Likelihood Functions
  • Low Back Pain / diagnostic imaging
  • Low Back Pain / etiology
  • Male
  • Predictive Value of Tests
  • Radionuclide Imaging
  • Retrospective Studies
  • Sacroiliac Joint / diagnostic imaging*
  • Sacroiliac Joint / pathology
  • Spondylitis, Ankylosing / complications
  • Spondylitis, Ankylosing / diagnostic imaging*
  • Spondylitis, Ankylosing / pathology