Abstract
Ultrastructural changes in the colorectal mucosa in response to chronic contact with the urine were demonstrated in outbred albino rat experiments. Oral correction with slightly alkaline sodium hydrocarbonate solution reduced the destructive effect of the urine on rat colorectal mucosa.
MeSH terms
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Animals
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Colon / anatomy & histology*
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Colon / pathology
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Humans
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Hydrogen-Ion Concentration
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Intestinal Mucosa* / pathology
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Intestinal Mucosa* / ultrastructure
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Male
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Rats
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Rectum / anatomy & histology*
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Rectum / pathology
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Sodium Bicarbonate / administration & dosage
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Time Factors
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Urine*
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Water-Electrolyte Balance