Cystic fibrosis and Crohn's disease: successful treatment and long term remission with infliximab

World J Gastroenterol. 2010 Apr 21;16(15):1924-7. doi: 10.3748/wjg.v16.i15.1924.


The association of cystic fibrosis and Crohn's disease (CD) is well known, but to date, there are very few cases in the literature of patients suffering from mucoviscidosis who have required treatment with infliximab. We report the case of a 23-year-old patient suffering from cystic fibrosis and severe CD treated successfully with infliximab without any infective complications or worsening of the pulmonary disease and with a long term (2 years) complete remission.

Keywords: Crohn’s disease; Cystic fibrosis; Infliximab.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / pharmacology
  • Antibodies, Monoclonal / pharmacology*
  • Colonoscopy / methods
  • Cystic Fibrosis / diagnosis*
  • Cystic Fibrosis / drug therapy*
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics
  • Female
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Inflammation
  • Infliximab
  • Lung Diseases / drug therapy
  • Lung Diseases / therapy
  • Remission Induction
  • Treatment Outcome


  • Anti-Inflammatory Agents
  • Antibodies, Monoclonal
  • CFTR protein, human
  • Immunosuppressive Agents
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • Infliximab