Use of the Mirena LNG-IUS and Paragard CuT380A intrauterine devices in nulliparous women

Contraception. 2010 May;81(5):367-71. doi: 10.1016/j.contraception.2010.01.010. Epub 2010 Feb 19.


Two intrauterine devices (IUDs) are available in the United States, the levonorgestrel-bearing intrauterine system (Mirena) and the copper-bearing T380A (Paragard). These devices have very low typical-use failure rates but are used by only a minority of women. In particular, there is concern about their use in nulliparous women. We review the available data to address common concerns about using IUDs in this population and show that nulliparous women desiring effective contraception should be considered candidates for IUDs.

Publication types

  • Practice Guideline

MeSH terms

  • Adolescent
  • Contraceptive Agents, Female / administration & dosage*
  • Female
  • Humans
  • Infertility, Female / etiology
  • Intrauterine Devices, Copper / adverse effects*
  • Levonorgestrel / administration & dosage*
  • Parity*
  • Pelvic Inflammatory Disease / etiology
  • Pregnancy
  • Uterine Perforation / etiology


  • Contraceptive Agents, Female
  • Levonorgestrel