HIV-1 subtype C transmission network: the phylogenetic reconstruction strongly supports the epidemiological data

Isabella Bon; Massimo Ciccozzi; Gianni Zehender; Carlo Biagetti; Gabriella Verrucchi; Alessia Lai; Alessandra Lo Presti; Davide Gibellini; Maria Carla Re

doi:10.1016/j.jcv.2010.03.021

HIV-1 subtype C transmission network: the phylogenetic reconstruction strongly supports the epidemiological data

J Clin Virol. 2010 Jul;48(3):212-4. doi: 10.1016/j.jcv.2010.03.021. Epub 2010 Apr 18.

Authors

Isabella Bon¹, Massimo Ciccozzi, Gianni Zehender, Carlo Biagetti, Gabriella Verrucchi, Alessia Lai, Alessandra Lo Presti, Davide Gibellini, Maria Carla Re

Affiliation

¹ Microbiology Section of the Department of Haematology and Oncologic Sciences, University of Bologna, Via Massarenti, 9-40138 Bologna, Italy.

PMID: 20400369
DOI: 10.1016/j.jcv.2010.03.021

Abstract

The sequence and times of the transmission events was reported after a hospital accident by a phylodynamic reconstruction of transmission network among four subjects. The dated tree allowed to date the transmission events with good approximation, the time point and direction of each transmission, estimated on the basis of the phylogeny, and agreed with the presumptive time of infection on the basis of clinical history-taking.

Publication types

Case Reports

MeSH terms

Cluster Analysis
Female
Genotype
HIV Infections / epidemiology*
HIV Infections / transmission
HIV Infections / virology*
HIV-1 / classification*
HIV-1 / genetics*
HIV-1 / isolation & purification
Humans
Infant, Newborn
Molecular Epidemiology
Phylogeny*
Polymorphism, Genetic*
Sequence Analysis, DNA
pol Gene Products, Human Immunodeficiency Virus / genetics

Substances

pol Gene Products, Human Immunodeficiency Virus