Treatment of a tardive dyskinesia patient with temporomandibular disorder: a case report

J Orofac Pain. Spring 2010;24(2):212-6.

Abstract

This case report presents a patient with tardive dyskinesia who also suffered from masticatory muscle pain and temporomandibular joint osteoarthrosis. The patient was treated with clozapine in gradually increasing doses and two injections of botulinum toxin type A one year apart. Involuntary movements of mandibular clenching and bruxing disappeared and pain was relieved to a great extent. Reappearances of dyskinetic movements and pain were observed during the follow-up period of 1.5 years.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antipsychotic Agents / adverse effects
  • Botulinum Toxins, Type A / therapeutic use
  • Bruxism / drug therapy*
  • Bruxism / etiology
  • Clozapine / therapeutic use
  • Dyskinesia, Drug-Induced / complications*
  • Dyskinesia, Drug-Induced / drug therapy
  • Facial Pain / drug therapy*
  • Facial Pain / etiology
  • Follow-Up Studies
  • GABA Antagonists / therapeutic use
  • Haloperidol / adverse effects
  • Humans
  • Male
  • Muscle Contraction / drug effects
  • Neuromuscular Agents / therapeutic use
  • Osteoarthritis / etiology
  • Recurrence
  • Schizophrenia / drug therapy
  • Temporomandibular Joint Disorders / drug therapy*
  • Temporomandibular Joint Disorders / etiology

Substances

  • Antipsychotic Agents
  • GABA Antagonists
  • Neuromuscular Agents
  • Botulinum Toxins, Type A
  • Clozapine
  • Haloperidol