Nutritional factors and pancreatic cancer: a case-control study from south-west Poland

Int J Cancer. 1991 May 30;48(3):390-4. doi: 10.1002/ijc.2910480314.


A population-based case-control study of diet and pancreatic cancer has been conducted in the Opole Voivodeship region in Poland, using 110 cases and 195 controls. A full diet history was used to estimate the daily intake of calories, fat, protein, carbohydrate, cholesterol, retinol, vitamin C, and fibre. There is a strong positive association with the intake of cholesterol with relative risks of 1.90, 3.77, and 4.31 for the 3 upper quartiles compared with the lowest (p, trend = less than 0.01). An inverse association was seen with vitamin C intake, with corresponding relative risks of 1.10, 0.30, and 0.37 (p, trend = less than 0.01). Weak inverse associations were seen with the intake of retinol and fibre. There is evidence of an inverse association with fat intake, particularly unsaturated fats, and of a positive association with the intake of carbohydrate and to a lesser extent, protein. These results further support the potential importance of dietary factors in the aetiology of cancer of the pancreas.

Publication types

  • Comparative Study

MeSH terms

  • Case-Control Studies
  • Cholesterol, Dietary
  • Demography
  • Diet*
  • Dietary Fats
  • Female
  • Humans
  • Interviews as Topic
  • Life Style
  • Male
  • Pancreatic Neoplasms / epidemiology*
  • Pancreatic Neoplasms / etiology
  • Pancreatic Neoplasms / mortality
  • Poland
  • Registries
  • Vitamin A


  • Cholesterol, Dietary
  • Dietary Fats
  • Vitamin A