Asymmetric hydrogenation of ketones catalyzed by a ruthenium(II)-indan-ambox complex

Chem Commun (Camb). 2010 Jun 14;46(22):3979-81. doi: 10.1039/b927028k. Epub 2010 Apr 21.

Abstract

(S,R)-Indan-ambox ligand and its ruthenium(II) complex have been prepared and successfully applied to asymmetric hydrogenation of prochiral simple ketones. A wide range of unfunctionalized ketones are reduced by Ru(II)-indan-ambox catalyst with excellent enantioselectivities (up to 97% ee).

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Coordination Complexes / chemistry*
  • Hydrogenation
  • Indans / chemistry*
  • Ketones / chemistry*
  • Ligands
  • Ruthenium / chemistry*
  • Stereoisomerism

Substances

  • Coordination Complexes
  • Indans
  • Ketones
  • Ligands
  • Ruthenium
  • indan