Abstract
Ketones and acyl silanes were reduced to the corresponding alcohols by a simple procedure employing anti-1,3-diol and a catalytic amount (5 mol %) of 2,4-dinitrobenzenesulfonic acid in benzene at reflux. Asymmetric induction reached up to >99% ee when a chiral pentane-2,4-diol of 97% ee was used.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemical synthesis*
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Alcohols / chemistry
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Benzenesulfonates / chemistry*
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Catalysis
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Glycols / chemistry*
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Ketones / chemistry*
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Molecular Structure
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Oxidation-Reduction
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Silanes / chemistry*
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Stereoisomerism
Substances
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Alcohols
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Benzenesulfonates
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Glycols
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Ketones
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Silanes
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2,4-dinitrobenzenesulfonic acid
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2,4-pentanediol