Realizing the promise of RNAi high throughput screening

Dev Cell. 2010 Apr 20;18(4):506-7. doi: 10.1016/j.devcel.2010.04.005.


Recently reporting in Nature, Collinet et al. describes the application of quantitative multiparametric methods to a genome-wide RNAi screen for regulators of endocytosis. The study illustrates the power of this approach beyond the identification of new endocytic components to providing insights into the design principles of the endocytic system.

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