Abstract
We report a patient with an overlap of relapsing polychondritis and Behcet disease whose cartilaginous inflammation and genital lesions were refractory to corticosteroids and immunosuppressants, but fully remitted with the tumor necrosis factor-alpha inhibitor, infliximab. We believe this case represents the first report of a response to a tumor necrosis factor inhibitor in a patient with mouth and genital ulcerations with inflamed cartilage syndrome.
MeSH terms
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Adult
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Anti-Inflammatory Agents / therapeutic use*
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Antibodies, Monoclonal / therapeutic use*
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Behcet Syndrome / complications*
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Behcet Syndrome / drug therapy*
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Humans
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Infliximab
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Male
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Polychondritis, Relapsing / complications*
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Polychondritis, Relapsing / drug therapy*
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Remission Induction
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Syndrome
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Tumor Necrosis Factor-alpha / antagonists & inhibitors*
Substances
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Anti-Inflammatory Agents
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Antibodies, Monoclonal
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Tumor Necrosis Factor-alpha
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Infliximab