Clinical effectiveness of transcervical polyp resection in women with endometrial polyps: randomized controlled trial

J Minim Invasive Gynecol. May-Jun 2010;17(3):351-7. doi: 10.1016/j.jmig.2010.01.019.


Study objective: To estimate the clinical effectiveness of transcervical resection of endometrial polyps.

Design: Randomized controlled trial (Canadian Task Force classification I).

Setting: University teaching hospital.

Patients: One hundred fifty premenopausal women with endometrial polyps.

Interventions: Either transcervical resection of the polyp or observation for 6 months.

Measurements and main results: There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11-1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat.

Conclusion: Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Blood Loss, Surgical
  • Chi-Square Distribution
  • Female
  • Humans
  • Hysteroscopy / methods*
  • Middle Aged
  • Patient Satisfaction
  • Patient Selection
  • Polyps / surgery*
  • Treatment Outcome
  • Uterine Diseases / surgery*