Quality of life among lower extremity peripheral arterial disease patients who have undergone endovascular or surgical revascularization: a case-control study

Eur J Vasc Endovasc Surg. 2010 Nov;40(5):618-25. doi: 10.1016/j.ejvs.2010.03.028. Epub 2010 Apr 24.


Objectives: To assess the quality of life (QoL) of peripheral arterial disease (PAD) patients who have undergone either percutaneous transluminal angioplasty (PTA) only and/or one or more surgical revascularizations.

Design: A postal questionnaire study in which a case-control methodology was applied.

Materials and methods: 131 patients with PTAs (mean age 70.7, SD 10.4 yrs; range 39-89, 58% men) and 100 with surgical revascularizations (mean age 67.8, SD 10.4 yrs; range 43-91, 62% men), in 1998-2003, and their age- and gender-matched controls were studied. The mean time since the last revascularization for PTA was 2.7, SD 1.3 yrs and for operated patients 3.5, SD 1.8 yrs. Ankle-brachial pressure index (ABI) and Mini-Mental-State Examination (MMSE) score were obtained from 70% of the patients. QoL was assessed using 15D Health-related QoL instrument, Rand-36 Physical Functioning subscale, 6-item Brief Social Support Questionnaire, Geriatric Depression Scale (GDS), Self-reported Life Satisfaction (LS) score, and one 'perceived state of health' question.

Results: Patients after endovascular and/or surgical revascularization (most with ABIs 0.5-0.89 and without cognitive impairment), had similarly lower QoL, GDS and LS indicated more depression than their controls.

Conclusion: Poor QoL and depression should be thoroughly considered, alongside proper follow-up and ABI-measurements.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Female
  • Humans
  • Lower Extremity / blood supply*
  • Lower Extremity / surgery
  • Male
  • Middle Aged
  • Peripheral Arterial Disease / surgery*
  • Quality of Life*
  • Surveys and Questionnaires*
  • Vascular Surgical Procedures