Vasculitis and infection with the human immunodeficiency virus

Rheum Dis Clin North Am. 1991 Feb;17(1):131-47.


Vasculitic syndromes associated with infection with the human immunodeficiency virus (HIV) would appear to represent a microcosm of the vasculitic spectrum. Reported cases have included polyarteritis nodosa-like illnesses, hypersensitivity vasculitis, lymphomatoid granulomatosis, primary angiitis of the central nervous system, and a number of miscellaneous disorders. The pathogenesis of these conditions is unclear, but some appear to be mediated in part by the HIV itself. Therapeutically, little clinical data exist to guide clinicians in the management of such patients, but aggressive approaches combining immunosuppressive therapy with assertive antimicrobial prophylaxis may be warranted.

Publication types

  • Review

MeSH terms

  • HIV Infections / complications*
  • HIV Infections / pathology
  • Humans
  • Vasculitis / complications*
  • Vasculitis / pathology