The latest neuroimaging findings in borderline personality disorder

Curr Psychiatry Rep. 2010 Feb;12(1):46-55. doi: 10.1007/s11920-009-0089-7.


This review provides an overview of the most recent neuroimaging findings in borderline personality disorder. The contributions of the structural and functional imaging studies of the past 3 years are presented to help us better understand this severe psychiatric disorder. There are three domains of functional imaging findings: 1) affective dysregulation; 2) the complex of dissociation, self-injurious behavior, and pain processing; and 3) social interaction. Knowledge of the neurobiological basis of borderline personality disorder has grown considerably. Therefore, these findings convey a good impression of the current findings from neuroimaging research in this disorder and also of the necessary next steps with regard to content and methodology.

Publication types

  • Review

MeSH terms

  • Borderline Personality Disorder / diagnosis
  • Borderline Personality Disorder / physiopathology*
  • Brain / physiopathology*
  • Brain Mapping
  • Humans
  • Magnetic Resonance Imaging