[Autoimmune hemolytic anemia associated with severe giant cell hepatitis]

An Esp Pediatr. 1991 Feb;34(2):149-51.
[Article in Spanish]


Autoimmune hemolytic anemia and severe giant cell hepatitis is an very uncommon association. Two patients aged 5 months and 2 years developed severe anemia, jaundice, hepatomegaly and splenomegaly. Laboratory tests demonstrated autoimmune hemolytic anemia and elevated amino-transferases. Diffuse giant cell transformation and distorted architecture was seen in liver biopsy. One patient had a cytomegalovirus infection. Early steroid therapy did not prevent fatal course with liver failure in one patient.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anemia, Hemolytic, Autoimmune / complications*
  • Anemia, Hemolytic, Autoimmune / immunology
  • Hepatitis / complications*
  • Hepatitis / immunology
  • Humans
  • Infant
  • Male