Indications for and barriers to preemptive kidney transplantation: a review

Transplant Proc. 2010 Apr;42(3):782-4. doi: 10.1016/j.transproceed.2010.02.031.


Preemptive kidney transplantation is the treatment of choice for end-stage renal disease. Compared with nonpreemptive transplantation, preemptive transplantation is significantly associated with improved kidney allograft survival in recipients of either cadaver or living-donor transplants. This seems to be related to better patient survival. It can be proposed to all patients, but still needs to be evaluated for repeat transplantation. The main barriers are organ-allocation policies and late referral of patients to transplantation centers.

Publication types

  • Review

MeSH terms

  • Cadaver
  • Graft Survival
  • Humans
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / adverse effects*
  • Kidney Transplantation / mortality
  • Kidney Transplantation / physiology
  • Living Donors
  • Retrospective Studies
  • Survival Rate
  • Tissue Donors
  • Transplantation, Homologous
  • Waiting Lists