Diffuse villous hyperplasia of the choroid plexus and its surgical management

J Neurosurg Pediatr. 2010 May;5(5):518-22. doi: 10.3171/2009.12.PEDS0960.


Diffuse villous hyperplasia of the choroid plexus (DVHCP) is a very rare cause of hydrocephalus in children. Only 12 cases of DVHCP have been reported in the literature. In this report the authors describe a new case of a patient with DVHCP who was diagnosed prenatally with hydrocephalus. In a comprehensive literature review and discussion, the authors also discuss radiological and histological characteristics of the reported cases, treatment approaches, and surgical modalities that have been used in the treatment of these patients.

Publication types

  • Case Reports

MeSH terms

  • Cerebrospinal Fluid Shunts
  • Child, Preschool
  • Choroid Plexus / pathology*
  • Choroid Plexus / surgery*
  • Device Removal
  • Echoencephalography
  • Endoscopy
  • Female
  • Follow-Up Studies
  • Humans
  • Hydrocephalus / diagnosis
  • Hydrocephalus / pathology*
  • Hydrocephalus / surgery*
  • Hyperplasia
  • Infant
  • Infant, Newborn
  • Lateral Ventricles / pathology
  • Lateral Ventricles / surgery
  • Magnetic Resonance Imaging
  • Male
  • Pregnancy
  • Prosthesis-Related Infections / diagnosis
  • Prosthesis-Related Infections / surgery
  • Reoperation
  • Ultrasonography, Prenatal
  • Ventriculoperitoneal Shunt