[Multiple ischemic strokes due to Borrelia garinii meningovasculitis]

Rev Neurol (Paris). 2010 Nov;166(11):931-4. doi: 10.1016/j.neurol.2010.03.010.
[Article in French]


The most frequent clinical manifestation of borreliosis in Switzerland is erythema migrans, with about 2500 patients each year. Neurological manifestations are rare, mostly hyperalgesic radiculitis (Bannwarth syndrome), aseptic meningitis or cranial nerve involvement. We report the first Swiss patient with meningovasculitis due to neuroborreliosis, with recurrent multiple ischemic strokes in multiple vascular territories. The treatment with ceftriaxone stopped the progression, but the patient is still suffering from severe invalidating cognitive disorders. We also comment on the pathophysiology and review the literature of other clinical cases.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Blotting, Western
  • Borrelia burgdorferi Group*
  • Brain Ischemia / etiology*
  • Brain Ischemia / pathology
  • Ceftriaxone / therapeutic use
  • Cognition Disorders / etiology
  • Cognition Disorders / psychology
  • Humans
  • Lyme Neuroborreliosis / complications*
  • Lyme Neuroborreliosis / pathology
  • Lyme Neuroborreliosis / psychology
  • Magnetic Resonance Imaging
  • Male
  • Meningitis / etiology*
  • Meningitis / pathology
  • Middle Aged
  • Stroke / etiology*
  • Stroke / pathology
  • Vasculitis, Central Nervous System / etiology*
  • Vasculitis, Central Nervous System / pathology


  • Anti-Infective Agents
  • Ceftriaxone