Epidemiology of immune-mediated inflammatory diseases: incidence, prevalence, natural history, and comorbidities

J Rheumatol Suppl. 2010 May;85:2-10. doi: 10.3899/jrheum.091461.


Immune-mediated inflammatory diseases (IMID) present a group of common and highly disabling chronic conditions that share inflammatory pathways. Several incidence and prevalence studies of IMID during the past decades have reported a considerable variation of the disease occurrence among different populations. Overall, the estimated prevalence of IMID in Western society is 5%-7%. This article provides an overview of studies of the incidence, prevalence, natural history, and comorbidities of IMID.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / epidemiology
  • Comorbidity
  • Disease Progression
  • Female
  • Global Health
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Incidence
  • Inflammation / drug therapy
  • Inflammation / epidemiology*
  • Inflammation / immunology
  • Male
  • Prevalence
  • Sex Distribution


  • Immunosuppressive Agents