Abstract
Pyruvate is the key substance controlling the formation of diacetyl, acetaldehyde, and acetate during alcoholic fermentation. Here we report the breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl alpha-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport. Mitochondrial function was involved in resistance to this substance and in the production of pyruvate by the mutants.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetates / metabolism
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Alcoholic Beverages
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Alcoholic Intoxication / genetics
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Alcoholic Intoxication / metabolism
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Alcoholics
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Biological Transport / genetics
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Breeding
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Fermentation / genetics
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Mitochondria / genetics
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Mitochondria / metabolism*
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Pyruvates / metabolism*
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Pyruvic Acid / metabolism*
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Saccharomyces cerevisiae / genetics
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Yeasts / genetics
Substances
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Acetates
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Pyruvates
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Pyruvic Acid