Caspase-12 and diabetic nephropathy: from mice to men?

J Am Soc Nephrol. 2010 Jun;21(6):886-8. doi: 10.1681/ASN.2010040394. Epub 2010 May 6.
No abstract available

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Apoptosis* / drug effects
  • Caspase 12 / genetics
  • Caspase 12 / metabolism*
  • Cell Line
  • Diabetic Nephropathies / metabolism*
  • Diabetic Nephropathies / pathology*
  • Disease Models, Animal
  • Endoplasmic Reticulum / physiology
  • Endoplasmic Reticulum Chaperone BiP
  • Gene Expression Regulation / drug effects
  • Heat-Shock Proteins / metabolism
  • Humans
  • Kidney Tubules, Proximal / metabolism*
  • Kidney Tubules, Proximal / pathology*
  • Mice
  • Polymorphism, Single Nucleotide / genetics
  • RNA, Small Interfering / pharmacology
  • Reactive Oxygen Species / metabolism
  • Transcription Factor CHOP / metabolism

Substances

  • Ddit3 protein, mouse
  • Endoplasmic Reticulum Chaperone BiP
  • Heat-Shock Proteins
  • RNA, Small Interfering
  • Reactive Oxygen Species
  • Transcription Factor CHOP
  • Caspase 12