Controlled drug release from porous materials by plasma polymer deposition

Chem Commun (Camb). 2010 Feb 28;46(8):1317-9. doi: 10.1039/b919840g. Epub 2010 Jan 5.

Abstract

In this communication, we present a novel approach for control of drug release from porous materials. The method is based on deposition of a plasma polymer layer with controlled thickness which reduces a pore diameter and, hence, defines the rate of drug release.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aluminum Oxide / chemistry*
  • Anti-Bacterial Agents / administration & dosage*
  • Delayed-Action Preparations / chemistry*
  • Electrochemistry
  • Polymers / chemistry*
  • Porosity
  • Vancomycin / administration & dosage*

Substances

  • Anti-Bacterial Agents
  • Delayed-Action Preparations
  • Polymers
  • Vancomycin
  • Aluminum Oxide